ADHD Medication Bioequivalents & Split Dose Options

Medication on Treatment Plan	Doses Available	Split Dose Available?	Bioequivalent Options (in order of formulary/prescribing preference by each medication but at clinical discretion)
Methylphenidate IR / Methylphenidate Hydrochloride (Generic)	5mg 10mg 20mg	Yes	Medikinet (IR)
Concerta XL	18mg 27mg 36mg 54mg	Yes	Delmosart Affenid XL Xenidate XL (clinical discretion) Xaggitin XL (clinical discretion)
Equasym XL	10mg 20mg 30mg	Yes	No direct bioequivalents available – clinical intervention required on any and all changes to treatment plan
Medikinet (Moderate Release)	5mg 10mg 20mg 30mg 40mg 50mg 60mg	Yes	Meflynate XL – not available in 5mg dose
Elvanse Elvanse (Adult)	20mg 30mg 40mg 50mg 60mg 70mg	Yes	Elvanse (Adult) – not available in 20mg dose Elvanse Lisdexamphetamine (Generic)
Amfexa Dexamfetamine (Generic)	5mg 10mg 20mg	Yes	Amfexa and Dexamfetamine (Generic) can be used interchangeably
Atomoxetine Capsules	10mg 18mg 25mg 40mg 60mg 80mg 100mg	Yes	Strattera Capsules Atomoxetine 4mg/1ml oral solution sugar free Strattera 4mg/1ml oral solution
Atomoxetine oral solution sugar free	4mg/1ml oral solution	N/A	Strattera 4mg/1ml oral solution Strattera Capsules Atomoxetine Capsules
Intuniv	1mg 2mg 3mg 4mg	Yes	Guanfacine MR
Circadin modified-release tablets*	2mg	N/A	Melatonin 2mg modified-release tablets (Generic)
Melatonin oral solution sugar free (instant release)*	1mg/ml	N/A	Melatonin Immediate Release tablets - 3mg and 5mg (generic) Adaflex (tablets) - 1mg, 3mg, 4mg, 5mg

*Please note that Circadin (Melatonin) is modified released and not interchangeable with instant release types of Melatonin. Please ensure that you check which type you a prescribed on your Treatment & Titration plan (TAT), Shared Care letter, or repeat prescriptions from your GP.